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Knowledge
Management for Influenza, Avian Influenza and Pandemic Influenza. |
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Genetic
characterization of influenza A viruses (H5N1) isolated
from 3rd wave of Thailand AI outbreaks. |
Amonsin
A, Chutinimitkul
S, Pariyothorn
N, Songserm
T, Damrongwantanapokin
S, Puranaveja
S, Jam-On
R, Sae-Heng
N, Payungporn
S, Theamboonlers
A, Chaisingh
A, Tantilertcharoen
R, Suradhat
S, Thanawongnuwech
R, Poovorawan
Y.
Faculty of
Veterinary Science, Chulalongkorn University,
Pathumwan, Bangkok 10330, Thailand.
Three major
outbreaks of avian influenza (AI) occurred
in Thailand. During the third episode in October
2005, we have isolated H5N1 viruses from one
human case and three poultry cases. The whole
genomes of AI viruses from human, chickens
and quail from the outbreaks were characterized.
Sequence analysis of eight gene segments revealed
that the 2005 H5N1 viruses isolated in October
2005 were closely related to those recovered
from chicken, tiger(s) and human(s) in January
and July 2004. In addition, the genetic changes
of the AI isolates at the HA cleavage site
have been observed.
PMID: 16935377
[PubMed - indexed for MEDLINE]
Virus
Res. 2006 Dec;122(1-2):194-9. Epub 2006 Aug 28.
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